The adventures of Superman's cousin in her own superhero career.
Cast: Melissa Benoist
In the epic series finale, Supergirl is joined by familiar faces from the past to help her stop Lex and Nyxly for good. Meanwhile, Alex and Kelly prepare to walk down the aisle.
Supergirl and the super friends take drastic action after a loved one is kidnapped by Nyxly and Lex; an unlikely ally steps in to help the team.
Esme has a fight at school, and Alex and Kara have a fight over how to settle it. Meanwhile, Nxyly searches for the Truth Totem.
When Lex Luthor appears by Nyxly's side, Supergirl and team must deal with the emotional fallout of facing their two biggest foes at the same time. Alex makes plans for the perfect proposal to Kelly, but work keeps getting in the way.
Nxyly goes after the Dream Totem, and Nia must join forces with her sister Maeve to stop the imp. Meanwhile, Supergirl worries that she's being pulled in too many different directions.
Supergirl continues to fight Nyxly for the remaining totems but after Nyxly kidnaps William, Supergirl realises she needs to take a more proactive stance to keep National City safe. Meanwhile, Alex faces the biggest challenge of her life.
Nxyly gets hold of the Humanity Totem, causing chaos throughout National City. Meanwhile, Esme meets her new foster family and Lena attempts to cast her first spell.
Supergirl and Nxyly battle for the Totem of Courage, and each get part of it. The part that Supergirl acquires causes chaos.
The people of the Heights are affected by the building collapse, and a new hero emerges to protect them.
Nxyly attempts to reunite the Allstone using Mxyzptlk as a power source. Meanwhile, Lena find out the truth about her mother.
Supergirl intervenes when a building in the Heights that was set aside for low income housing is suddenly at risk to be sold to a major corporation. Supergirl recruits Orlando to help her win over the city, but things go awry when Nyxly shows up. Meanwhile, Nia trains with her mother.
Kelly meets Joey, a young orphaned alien boy, who is acting out in foster care because he fears there is something wrong with his brother Orlando, who is incarcerated. Kelly asks Kara to help her investigate and they stumble upon abuse at the prison. Meanwhile, Nyxly crashes one of Nia's dreams and asks her for help.
Kara copes with returning to Earth, with Zor-El posing as her uncle.
As the Super Friends brave the Phantom Zone to bring Supergirl home, each member of the team is confronted by visions of their worst fear.
Young Kara experiences kryptonite for the first time, Nia and Brainy are trapped by invading aliens, and a young Cat Grant may be the reason Supergirl never gets out of the Phantom Zone.
Brainiac-5 and Nia time-travel to 1990 Midvale to get a sample of Kara's DNA.
Supergirl finds an opportunity to escape from the Phantom Zone but it comes with some dangerous strings attached; Lena joins the Super Friends on a mission but finds she disagrees with their plan of action.
Supergirl makes a new ally. Lena and Lex battle for control of Luthor Corp.
While Lex faces trial for his crimes, J'onn and Alex try to access the Phantom Zone to rescue Supergirl.
Lex attempts to take control of half the population of Earth, as the first step in his plan to "fix" the universe.