Grey\'s Anatomy is a hospital drama that focuses on Meredith Grey (Ellen Pompeo), one of several third year residents at a Seattle Grace hospital. Along with her colleagues, Meredith struggles to maintain relationships while staying sharp at work. The professional roles and real lives of a diverse group of surgeons collide unexpectedly in this Golden Globe-winning ABC television drama.
Cast: Ellen Pompeo, Sandra Oh, Justin Chambers, Chandra Wilson, James Pickens Jr., Patrick Dempsey, Katherine Heigl, T.R. Knight, Sara Ramirez, Eric Dane, Chyler Leigh, Isaiah Washington, Kate Walsh, Kevin McKidd, Jessica Capshaw
The chief tries to determine who's responsible. Callie presses George about his feelings. Derek and Meredith have to make a decision about Doc. The interns are charged with pleasing the chief's niece.
The struggle to get Denny a heart continues. Christina gets to run her own trauma. Shepherd is responsible for a friend's life. The Chief's niece is brought to the ER by his wife.
George works a case with Derek, while Meredith works with Callie. Meanwhile, Finn gives an update on Doc's health, and Burke and Izzie keep looking for a heart for Denny.
Derek lets his emotions run away from him, and Burke and Izzie make a new suggestion to Denny. Menanwhile, the interns treat a family involved in an auto accident, Callie makes Meredith and Izzie uncomfortable, and Addison strikes back at Alex.
While Izzie grills George about the personal details of his life, Addison takes Alex to task about a sensitive case. Also, Burke feels the pressure when he treats his musical hero, and Meredith considers dating a hunky vet.
George begins to overstay his welcome at Burke and Cristina's apartment. Cristina takes a seminar and discovers that Chief Webber is taking it too. Meanwhile, Meredith learns a startling secret about her father, Bailey worries her colleagues will not treat her the same now that she's a mother, and Alex gets a lesson in bedside manners.
A complication from the LVAD surgery puts Denny in the OR during a death cycle, Cristina maneuvers to get George kicked out, and an old mentor of the Chief's is admitted for treatment.
Cristina babysits for Bailey and doesn't take to it well at all. Meanwhile, Addison and Derek come to terms with their relationship, and Denny keeps coming between Alex and Izzie.
Karma figures large in the minds of most of the staff for various reasons, and Meredith and George face the repercussions of their actions.
Derek and Addison are shaken by the arrival of someone from their past. Meanwhile, Burke learns Cristina's secret, and Meredith delves into her family's dirty laundry.
While the man with the bomb lodged in his chest remains in Burke's OR, Bailey's injured husband remains in Derek's. Meanwhile, Bailey still hasn't delivered her baby.
The lives of everyone in the OR are threatened when a patient enters with a bomb inside of him... and a young paramedic with her arm inside the cavity is the only thing keeping it from going off.
The nurses strike, leaving the doctors unprepared for their extra duties. Cristina and Burke have to define their work relationship, Izzie relates to a pregnant teenager, and Meredith finds parallels to her mother in a case requiring her to remove life support.
Meredith has to choose between her dog and her roommates, Alex gets his board results, and Bailey's pregnancy may be at risk.
Izzie realizes that she is attracted to her patient with a heart condition. George treats Bex, a hermaphrodite. Meredith's mother gets a special visitors. Derek and Addison's relationship is still rocky.
Christmas brings a range of holiday spirits, from Ã¼ber-cheer to Scrooge, and holiday maladies.
The mother of the quints blames herself, Izzy becomes attached to her patient, Karev must face the consequences of his actions, and Cristina cares for an inmate desperate to stay at the hospital.
Meredith's one night stand causes complications when he shows up at the hospital with an embarrassing problem, Burke tries to push Cristina toward the next step, and Alex's problems affect his performance.
Thanksgiving sends the occupants of the house in different directions: Meredith escapes to the hospital, George goes hunting with his family, and Izzie throws a dinner that it appears no one is coming to.
Freinds of Derek and Addison come from New York, because the woman wants a preventative hysterectomy and mastectomy because she is afraid of cancer. Meanwhile, George is freaking out because he almost got hit by a man falling from a roof.
Addison and Derek go to marriage counseling. Derek says that he's finished with Meredith. Meanwhile, Meredith becomes the main gossip topic in the hospital and Izzie and Christina discover a pregnant man. Preston tells the Chief about him and Christina and Alex finally kisses Izzie.
A train wreck brings multiple casualties to Seattle Grace, leaving Meredith hanging for her answer. Meanwhile, Alex finds working without his "mojo" a disheartening experience, and Yang searches high and low for a missing appendage.
A storm rages in Seattle. Izzie is very disappointed by her date with Alex, and Meredith is upset with Derek. They both complain to George, which drives him crazy. At the hospital, Cristina has a patient that uses porn as a pain killer and Meredith takes care of an Asian girl who needs to see a Shaman before surgery. There is a power shortage and George and Alex are stuck in an elevator with a critical patient.
Meredith deals with her mother's illness and with her complicated relationship withe the Shepherds. There is still hope for her and Derek, because he didn't sign the divorce papers, but he himself does not know what to do. Meanwhile Burke and Christina also deal with their relationship and Izzie and Alex go for a date. But Alex is nervous because he might lose his M.D. so he does not act as himself.
Meredith's mother is admitted to the hospital, revealing that the once great surgeon now has Alzheimer's disease. Menwhile, Christina faints during operation and needs immediate care. She loses her baby due to complications and becomes a patient. Burke finally finds out about her pregnancy when it's too late. Mrs Grey gives hell to George because she thinks he is her husband, but George copes with it.
After a fatal car accident, a man, a woman and their son are patients in the Seattle Grace hospital. The injuries of the mother reveal a family secret. Another patient has swallowed something strange, but refuses to reveal what. On the personnel level, Meredith and Cristina try to get along with the ending of their relationships.
Barowner Joe collapses in his bar and needs to undergo an 200.000$ surgery to survive. Since Joe has no insurance George tries to find a way to get the money together. Dr. Webber is recovering from his operation and appointed Burke as his replacement. Burke has now to face the consequences that come with the responsibilities of his new position.