Owen runs into someone very special from his past. Izzie employs her fellow doctors in a medical game made to help teach the interns. Naomi, Sam and Addison rush Archer to Seattle Grace and meet with Derek and Mark to save his life.
Cast: Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers, T.R. Knight, Chandra Wilson, James Pickens Jr., Sara Ramirez, Eric Dane, Chyler Leigh, Kevin McKidd, Patrick Dempsey, Kate Walsh, Audra McDonald, Taye Diggs